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Dr S OUNZAIN > Publication Scientifique

Samir Ounzain
CHUV, University of Lausanne
Verified email at
ncRNAslncRNAsgene regulatory networkscardiac developmentdisease and regeneration


  • Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs

S Ounzain, R Micheletti, T Beckmann, B Schroen, M Alexanian, I Pezzuto, ...
European heart journal 36 (6), 353-368 103 2014

  • Functional importance of cardiac enhancer-associated noncoding RNAs in heart development and disease

S Ounzain, I Pezzuto, R Micheletti, F Burdet, R Sheta, M Nemir, ...
Journal of molecular and cellular cardiology 76, 55-70 69 2014

  • CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis

S Ounzain, R Micheletti, C Arnan, I Plaisance, D Cecchi, B Schroen, ...
Journal of molecular and cellular cardiology 89, 98-112 47 2015

  • Small and long non-coding RNAs in cardiac homeostasis and regeneration

S Ounzain, S Crippa, T Pedrazzini
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (4), 923-933 45 2013

  • Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury

SP Barry, S Ounzain, J McCormick, TM Scarabelli, C Chen-Scarabelli, ...
International journal of cardiology 163 (3), 326-334 32 2013

  • The promise of enhancer-associated long noncoding RNAs in cardiac regeneration

S Ounzain, T Pedrazzini
Trends in cardiovascular medicine 25 (7), 592-602 30 2015

  • Discovery and functional characterization of cardiovascular long noncoding RNAs

S Ounzain, F Burdet, M Ibberson, T Pedrazzini
Journal of molecular and cellular cardiology 89, 17-26 21 2015

  • Hsp-27 induction requires POU4F2/Brn-3b TF in doxorubicin-treated breast cancer cells, whereas phosphorylation alters its cellular localisation following drug treat...

R Fujita, S Ounzain, ACY Wang, RJ Heads, VS Budhram-Mahadeo
Cell Stress and Chaperones 16 (4), 427-439 15 2011

  • STARS is essential to maintain cardiac development and function in vivo via a SRF pathway

NW Chong, AL Koekemoer, S Ounzain, NJ Samani, JT Shin, SY Shaw
PloS one 7 (7), e40966 14 2012

  • Comparative in silico analysis identifies bona fide MyoD binding sites within the Myocyte stress 1 gene promoter

S Ounzain, CS Dacwag, NJ Samani, AN Imbalzano, NW Chong
BMC molecular biology 9 (1), 50 14 2008

  • Cardiac expression of ms1/STARS, a novel gene involved in cardiac development and disease, is regulated by GATA4

S Ounzain, S Kobayashi, RE Peterson, A He, A Motterle, NJ Samani, ...
Molecular and cellular biology 32 (10), 1830-1843 12 2012

  • Super-enhancer lncs to cardiovascular development and disease

S Ounzain, T Pedrazzini
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1953-1960 9 2016

  • Proliferation-associated POU4F2/Brn-3b transcription factor expression is regulated by oestrogen through ERa and growth factors via MAPK pathway

S Ounzain, S Bowen, C Patel, R Fujita, RJ Heads, VS Budhram-Mahadeo
Breast Cancer Research 13 (1), R5 8 2011

  • The long noncoding RNA Wisper controls cardiac fibrosis and remodeling

R Micheletti, I Plaisance, BJ Abraham, A Sarre, CC Ting, M Alexanian, ...
Science translational medicine 9 (395), eaai9118 6 2017

  • Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways

S Crippa, M Nemir, S Ounzain, M Ibberson, C Berthonneche, A Sarre, ...
Cardiovascular research 110 (1), 73-84 5 2016

  • Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression

I Plaisance, S Perruchoud, M Fernandez-Tenorio, C Gonzales, S Ounzain, ...
JACC: Basic to Translational Science 1 (6), 472-493 2 2016

  • New Lncs to mesendoderm specification

M Alexanian, T Pedrazzini, S Ounzain
Journal of thoracic disease 9 (Suppl 1), S5 1 2017

  • Long non-coding RNAs in heart failure: a promising future with much to learn

S Ounzain, T Pedrazzini
Annals of translational medicine 4 (15) 1 2016

  • Divergent Paths Lnc Cell Fates

S Ounzain, T Pedrazzini
Cell stem cell 18 (5), 561-562 1 2016

  • Profound hyperglycemia in knockout mutant mice identifies novel function for POU4F2/Brn-3b in regulating metabolic processes

S Bitsi, H Ali, L Maskell, S Ounzain, V Mohamed-Ali, ...
American Journal of Physiology-Endocrinology and Metabolism 310 (5), E303-E312 1 2016

  • A transcribed enhancer dictates mesendoderm specification in pluripotency

CC Ting, CE Friedman, D Maison, D Maric, D Villeneuve, F Burdet, ...
Nature communications 8 (1), 1806 2017

  • Diagnostic, prognostic and therapeutic uses of long noncoding rnas for heart disease and regenerative medicine

S Ounzain, T Pedrazzini
US Patent App. 15/105,319 2014

  • Differentiation-dependent telomeric long non-coding transcription in a model of skeletal myogenesis

S Brouilette, S Ounzain, V Sawhney, K Yashiro, Y Shintani, K Takahashi, ...
bioRxiv, 000679

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